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عمومی::
غلظت پیشگیریکننده از رشد سویهی جهشیافته
By themselves none of the plasmid-mediated quinolone resistance determinants raises the MIC above the CLSI designated susceptibility breakpoint, but they raise mutant prevention concentration (MPC) as well as the MIC and facilitate the selection of a variety of additional chromosomal mutations of higher MIC via activation of efflux pumps and altered membrane LPS .
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